WHAT IS OROMUCOSAL DELIVERY SYSTEM?

Oromucosal delivery systems involve administering drugs or substances through the mucous membranes of the oral cavity, such as the mouth or gums. This route allows for direct absorption into the bloodstream, bypassing the digestive system.

Benefits of oromucosal delivery system:

Rapid Absorption: The mucous membranes in the oral cavity allow for quick absorption, leading to faster onset of action compared to oral ingestion.

Enhanced Bioavailability: Dissolution and absorption into systemic circulation through oral cavity and eliminating first-pass metabolism, results in higher bioavailability and more efficient therapeutic outcomes.

Avoidance of First-Pass Metabolism: Substances absorbed through oromucosal routes bypass the liver initially, reducing the risk of metabolism and enhancing bioavailability.

Compliance: Oromucosal formulations are often user-friendly, making it convenient for administration without the need for mixing with food or water.

Dose Precision: The direct delivery allows for better control over dosing, promoting more accurate and consistent administration.

Reduced GI Side Effects: Since oromucosal delivery avoids the digestive tract, it can minimize gastrointestinal irritation and side effects associated with oral medications.

Treatment of Acute Conditions: The rapid onset of action makes oromucosal delivery suitable for managing acute conditions where quick relief is essential.

Due to having a rich blood supply and being highly vascularized in the oral mucosa, active ingredients are immediately absorbed through the oral buccal mucosa and directly enter the systemic circulation, bypassing the gastrointestinal tract and first-pass metabolism in the liver. This results in a rapid onset of action with a more comfortable and convenient delivery route.

The Oral Mucosa: The oral mucosa is characterized by its high permeability, attributed to the non-keratinized nature of the buccal epithelium. Additionally, the limited development of tight junctions and a substantial surface area contribute to the effortless and rapid absorption of active ingredients into the bloodstream.

Easy and fast transportation of active ingredients from the oral mucosa into the bloodstream.

OROMUCOSAL DELIVERY SYSTEMS OPTIMIZE ABSORPTION, ENHANCE BIOAVAILABILITY, AND CONSEQUENTLY, FACILITATE RAPID AND EFFECTIVE ACTIONS

ORALLY DISSOLVING FILM TECHNOLOGY

A Novel and Emerging Pharmaceutical Dosage Form: Fast Dissolving Oral Strips (FDSs)

Zoeuticals’ FDSs, a product of advanced oromucosal delivery system with nanotechnology, consist of single, flavorful sheets containing essential natural active ingredients. Placed in the mouth, these strips adhere and dissolve rapidly without the need for chewing, ensuring swift absorption. The evident enhancement in absorption rate and bioavailability, coupled with a noticeable taste-masking effect, underscores the impact of our oral strips.